Vial Processing

SP Scientific’s PennTech manufactures advanced aseptic vial processing equipment that is uniquely engineered to outperform. A special emphasis is put on high quality, small scale, and efficient design principles. Today, SP PennTech is the only company in the United States to manufacture complete aseptic vial processing lines. Special emphasis is put on simplistic, yet robust design, adherence to cGMP guidelines, and quality, not only of the machines, but also of the supporting validation documents.

Vial Washers

The objective of vial washing is to remove particulate matter and microorganisms. Traditional vial washers employ moving parts (e.g., grippers with springs, penetrating spray needles, chains, moving rods) in the washing chamber, which all generate particulate matter. SP PennTech washers have only two moving parts inside the washing chamber and their main drive is servo-driven. They also cover the full range of pharmaceutical vials, from 2-100ml, both glass and plastic.

Each vial format has an HMI selected “recipe” with specific settings for such variables as spraying time and indexing time. Water for injection (WFI) can be recycled, filtered and used a second time and intermittent spraying further reduces water consumption. These factors result in a highly efficient vial washing process. For over 20 years, SP PennTech has optimized and perfected the art of vial washing.

CLICK HERE - Vial Washer Product Portfolio (RW-250 & RW-500)

CLICK HERE - Vial Washer Product Portfolio (RW-800 & RW-1150)

Tunnel Loaders

SP PennTech offers a uniquely simple, yet effective, method of loading vials into the tunnel. The key here is to keep positive control over the vials at all times. Unlike “reverse funnels” and timing screws, vials are collected from the vial washer into a “pack” before gently being pushed into the tunnel by an oscillating pushing block. No format parts are required and the pushing motion is part of the vial recipe in the PLC. This is essentially a set-it-and-forget-it automatic process requiring no operator intervention.

CLICK HERE - Tunnel Loader Product Portfolio (TP-1 & TP-4)

Sterilization Tunnels

The typical operating temperature of the tunnel is 320° C. At this temperature it takes 9.5 seconds to reduce the bacterial endotoxin level by 1-log. A 4-log reduction will take 38 seconds, and a 6-log reduction in bacterial endotoxin 57 seconds.

Heat is generated by silicon controlled rectifier (SCR) heating elements. Depending on the format, vials stay inside the sterilizing/depyrogenation chamber for approximately 6-10 minutes. The recirculated hot air is blown at a speed of approximately 0.7 m/s over the vials and remains within 2°C of its setpoint.

CLICK HERE - Sterilization Tunnel Product Portfolio 

Aseptic Fillers

The FS(C)-series is comprised of single and dual filling and stopper-inserting machines, with or without the capping function, and is designed for 2ml to 100ml vials and offers an output of up to 200 vials per minute. The compact in-line design features Allen Bradley components and is equipped with servo-motors. Format changeovers are highly automated using PLC-stored recipes per vial format.

CLICK HERE - Aseptic Filler Product Portfolio (FS-22 ,& FSC-1R)

Capping Machine

SP PennTech capping machines feature all stainless steel construction with tempered glass doors and windows and stainless steel hinges with built-in safety switches. Their sanitary, raised track conveyor makes cleaning easy. No stopper, no cap pick up. There is a reject station available. The compact and versatile design features the electrical cabinet located within the frame of the machine and 13, 20 and 32mm flip-off caps with PLC-assisted changeover and a menu-driven operation through AB PLC and AB PanelView 1000 Plus.

CLICK HERE - Capping Machine Product Portfolio (AC-6)

External Vial Washers

Vials filled with potent drugs such as antibiotics, cytotoxics and cytostatics need to be cleaned before further processing. SP PennTech’s unique solution to this requirement is achieved by enclosing the aluminum cap between two opposed belts. The seal that is created prevents the cleaning agent from entering the cap area, thereby eliminating potential future bacterial contamination.

Another advantage of sealing the cap is the application of pressurized water for cleaning the entire vial body, including the bottom. Operation is menu-driven through the human machine interface (HMI). PLC-controlled servo motors automatically set the output rate, the vial height and the water/air flow per vial size. The changeover to a different cap or vial format is tool-less and can be accomplished within 15 minutes.

CLICK HERE - External Vial Washers Product Portfolio (EVW 60 / 100)

CLICK HERE - External Vial Washers Product Portfolio (High Output External Vial Washer)

Lyophilizer Loading Equipment

Lyophilizer Loading Equipment features consistent loading with the same number of vials per tray, and non-stop loading, even when replacing a full tray. Automatic containment ring lowering systems for freeze drying applications and camera inspection to ensure same cap color/format and vial configuration options are available.

CLICK HERE - Lyophilizer Loading Equipment Product Portfolio

Trayloaders

If vial collection is required, SP PennTech has customized trayloaders for your application and your tray format. They offer a single trayloader up to 200 vials/minute or a dual trayloader up to 400 vials/ minute with a vial range from 2-500ml vials/bottles. No format/change parts are required. The trayloaders are menu-driven with a PLC-assisted changeover and feature automatic nesting.

CLICK HERE - Trayloaders Product Portfolio (TL-100 / 200)

CLICK HERE - Trayloaders Product Portfolio (HSTL-200)

Peripheral Equipment

To integrate your aseptic filling line you will need peripheral equipment, such as: a Multi-Lane Accumulating Table, a Sanitary Raised-Track Conveyor, a Through-The-Wall Conveyor, a Down-Vial Reject Block, a Rotary Accumulating and Transfer Table, a Side-By-Side Conveyor Transfer, or a Vial Inverting Table.

CLICK HERE - Peripheral Equipment (Sanitary Conveyor & Accumulation Table)